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Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation that produces them likely to benefit from naltrexone, in contrast to about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are still available online ( inside the journal Neuropsychopharmacology and you will be published in the upcoming print edition from the journal. Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err on the side of caution and allow FDA do its job and demand some research be done so the public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their own medications. Researchers found out that participants using this drug for the year, dropped a few pounds within one month and have kept the body weight off through the 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of several active ingredient, which can make them far better and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that since right now there aren't any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise hypertension and heart rate, and really should not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. Acamprosate also works to eliminate the desire to drink through the elimination of the the cravings for having a drink. The major difference between Naltrexone and Acamprosate is Acamprosate is not yet accessible in the United States. While it may be widely studied in Europe the complete chemical reason that it works is still unknown. It is believed that it interferes with receptors in the brain which process glutamate, which in essence alters just how ones body reacts to alcohol intake. Several of the European studies show a lot of promise with Acamprosate for the reason that some of the patients had a nearly double success rate for staying sober.